Historical trauma, loss of territory, violence, discrimination, economic precariousness, and the breakdown of political, religious, and social institutions have had a significant impact on the mental health of Indigenous peoples in the Amazon region.Organización de los Pueblos Indígenas de la Amazonía Colombiana (OPIAC) will take an intercultural approach that combines western and Indigenous worldviews to promote emotional and psychological wellbeing in Indigenous youth in the department of Vaupés. Indigenous youth will be trained as community mental health promoters who will identify mental health needs and design and implement mental health promotion initiatives in their communities with support from elders.