Nexa
Nexa is a climate and health initiative co-led by Grand Challenges Canada and the Science for Africa Foundation, in collaboration with a global consortium of partners and funders.
We are investing in bold, innovative solutions across Africa, Latin America, and the Caribbean that enable local health actors to turn climate-driven health risk signals into timely health service delivery action, reducing health harms from mosquito-borne infections, extreme heat, and poor air quality.
All proposals must be submitted via the Fluxx portal by July 22, 2026, at 2:00 p.m. ET (6:00 p.m. UTC).

Funding opportunity
Funding focus
Applications must directly address at least one of the following areas of focus:
- Climate-informed early warning and monitoring systems: Innovations that allow health actors to anticipate and respond to the impacts of heat, poor air quality, and/or changing mosquito ecology (resulting in the accelerated spread of malaria and dengue infections).
- Climate-responsive patient care delivery: Innovations that strengthen local response to mosquito-borne infection harms, and/or the health impacts of heat and poor air quality.
What are we investing in?
- Proof of Concept innovations: meaning the testing of early-stage ideas, methods, or products. For more detail on how Nexa defines Proof of Concept, please refer to this helpful guide: Our Investment Approach.
- Transition to Scale innovations: meaning approaches that have already been tested, proven to be effective, and are now ready to be implemented more widely. For more detail on how Nexa defines Transition to Scale, please refer to this helpful guide: Our Investment Approach.
What is the funding amount?
- Proof of Concept funding amounts are up to $200,000 USD per innovation.
- Transition to Scale funding amounts will range between approximately $250,000 – $2,000,000 USD per innovation at the Nexa partners’ discretion, depending on the maturity of the innovation.
Who can apply?
- For Proof of Concept funding:
- Applicant organizations must be incorporated or equivalent in an eligible country in Africa, or in Brazil only (not elsewhere in Latin America or the Caribbean). See the complete list of eligible countries in Appendix B of the Funding Opportunity.
- For Transition to Scale funding:
- Applicant organizations can be incorporated or equivalent in any country but must implement in eligible countries in Africa, Latin America, or the Caribbean. See the complete list of eligible countries in Appendix B of the Funding Opportunity.
How to apply
Applications must be submitted via Grand Challenges Canada’s online portal (Fluxx). We will not accept applications submitted via any other channel. For more information on how to submit an application see our Guidance on How to Apply.
All proposals must be submitted via the Fluxx portal by July 22, 2026, at 2:00 p.m. ET (6:00 p.m. UTC).
Key documents
Please read all of the eligibility criteria and competition details in the full Funding Opportunity document before applying.
For more information about Nexa, please visit www.nexaclimate.org
For questions related to the content of this funding, please visit the Apply for Funding page on our website for:
- Guidance on How to Apply
- More information on Nexa’s investment approach via Grand Challenges Canada’s helpful guide: Our investment approach
- Innovator Resources
- For anything not addressed through these resources, the Funding Opportunity document, or the information session, reach out to OpenCompetitions@grandchallenges.ca
Key Documents:
Information Session
Join the Grand Challenges Canada and the Science for Africa Foundation for a brief overview of the funding opportunity on Monday, July 6, 2026, at 9:00 a.m. ET (2:00 p.m. UTC).
The session will be followed by an open Q&A session for potential applicants. Attendees are expected to have carefully reviewed the funding opportunity document and all linked resources in advance, as the session will not a substitute a thorough review of those materials.
Please note that we cannot provide feedback on specific proposed innovations, including assessments of relevance, fit, or innovativeness.


































