Project Lead(s): Margaret Ng'ang'a
Issue
Most low-cost diagnostic devices are made from non-degradable plastics, making them difficult to dispose of and posing a risk to the very population the diagnostic kits are aiming to help.
The growing numbers of such non-degradable devices mean they pose a serious threat to bio-safety.
Solution
The goal of the project undertaken in Kenya was to develop an incinerable and biodegradable casing for low-cost diagnostic devices.
The quality of cellulosic biomaterials (tree barks and other plant-based fibrous materials) were tested to determine the most suitable materials for more study.
Chemical modification produced ultra-hydrophobic materials that were ideal for use with biological fluids.
Outcome
Prototypes developed during this work compared well with commercially available devices.
In addition, the paper casings, once made hydrophobic, do not interfere with the test-strips, but rather act as energy sources to degrade these devices and avoid biohazard exposure to unsuspecting populations, making them environmentally benign.
The team now plans to:
· Complete laboratory testing of the biodegradation of the device and establish alternative reagents to make the paper hydrophobic
· Develop a new casing with a minimized amount of paper
· Manufacture paper-based diagnostic devices in Kenya
· Educate physicians about the process
· Collaborate with partners to develop a business plan and bring together a strong team of technology, medical and business leaders to help establish the business and go through the regulatory process in Kenya.