The accurate diagnosis of active TB, including drug-resistant forms, requires methods that can detect very small quantities of DNA from the TB bacteria in the infected person. Using destabilizing DNA that can be routinely made with common reagents, a small fragment of the TB DNA sequence can be amplified and detected without temperature cycling.
|Program||Stars in Global Health Round 3|
|Institution||University of Alberta|
|Implementation Country||South Africa, Zimbabwe|
|Implementation Region||Sub-Saharan Africa|
|Priority||Infectious Diseases, Tuberculosis|